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Ozonated Glycerin — ozonized glycerin

Ozonated glycerin is one of the newest formats in ozone skincare, and one of the least understood. This guide exists to fix that. It covers what ozonated glycerin is, how it differs chemically from ozonated oils, what the published research does and doesn't show, and how to use it in a daily routine.

We make Glyzine(TM), our ozonated glycerin, at a stated concentration of approximately 10,000 ppm from USP-grade organic vegetable glycerin in an ISO Class 5 cleanroom environment. It is, as far as we know, the first ozonated glycerin backed by an independent LC-MS chemical profile, and we publish what that analysis can and cannot tell us. The science on this ingredient is early - a small number of controlled cosmetic studies and a growing body of laboratory work - and these articles say so plainly.

Start with "What Is Ozonated Glycerin" if you're new, or the chemical profile if you want the chemistry first.
5 articles

Is Ozonated Glycerin Safe?

Ozonated glycerin is well-tolerated by most people when made from high-purity ingredients and produced correctly. Here’s what the evidence shows — and what to watch for.

Nattha Wannissorn, PhD · Updated August 2026

Glyzine Skincare Routine: How to Use Ozonated Glycerin for Skin

Ozonated glycerin offers a unique approach to ozone skincare — water-soluble, odor-free, and non-greasy. Learn how to use Glyzine in your daily routine and what the emerging res...

Nattha Wannissorn, PhD · Updated August 2026

Ozonized Glycerin vs. Ozone Oil: What Are the Differences?

Ozonized glycerin and ozone oil are both ozone-infused products, but their chemistry, texture, and use cases are fundamentally different. Here's how to choose between them.

Nattha Wannissorn, PhD · Updated August 2026

What's Really in Ozonized Glycerin? | Chemical Profile

SimplyO3 shares what independent analysis revealed about the chemical composition of ozonized glycerin — including glyceric acid, glycolic acid, and why pure oxygen matters in p...

Nattha Wannissorn, PhD · Updated August 2026

What is Ozonated Glycerin (Glyzine)?

Ozonated glycerin combines ozone's oxidative chemistry with glycerin's natural humectant properties — resulting in a water-soluble, odor-free format for ozone wellness. Learn wh...

Nattha Wannissorn, PhD · Updated August 2026