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Ozonated Glycerin — ozone wellness

Ozonated glycerin is one of the newest formats in ozone skincare, and one of the least understood. This guide exists to fix that. It covers what ozonated glycerin is, how it differs chemically from ozonated oils, what the published research does and doesn't show, and how to use it in a daily routine.

We make Glyzine(TM), our ozonated glycerin, at a stated concentration of approximately 10,000 ppm from USP-grade organic vegetable glycerin in an ISO Class 5 cleanroom environment. It is, as far as we know, the first ozonated glycerin backed by an independent LC-MS chemical profile, and we publish what that analysis can and cannot tell us. The science on this ingredient is early - a small number of controlled cosmetic studies and a growing body of laboratory work - and these articles say so plainly.

Start with "What Is Ozonated Glycerin" if you're new, or the chemical profile if you want the chemistry first.
2 articles

Is Ozonated Glycerin Safe?

Ozonated glycerin is well-tolerated by most people when made from high-purity ingredients and produced correctly. Here’s what the evidence shows — and what to watch for.

Nattha Wannissorn, PhD · Updated August 2026

What is Ozonated Glycerin (Glyzine)?

Ozonated glycerin combines ozone's oxidative chemistry with glycerin's natural humectant properties — resulting in a water-soluble, odor-free format for ozone wellness. Learn wh...

Nattha Wannissorn, PhD · Updated August 2026